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FDA Says No Connection Between Paxlovid and Rebound, Drug for MS May Function Covid AntiviralFrequent Enterprise Traveler

Delta plane at New York’s JFK airport

Good morning. That is Jonathan Spira reporting. Right here now the information of the pandemic from throughout the globe on the 1,a centesimal day of the pandemic.

Simply because somebody is a tech innovator doesn’t imply he isn’t additionally a creep or worse.

Steve Kirsch, an American entrepreneur, is certainly one of two individuals who independently invented the optical mouse in 1980 and created the search engine Infoseek, which was launched in 1994.  Extra lately he has been a promoter of misinformation about coronavirus vaccines in addition to a philanthropic supporter of medical analysis.

In 2020, the primary full 12 months of the pandemic, Kirsch created a analysis fund for potential remedies for SARS-CoV-2, pouring $1 million into the Covid-19 Early Therapy Fund, in keeping with a report by the MIT Expertise Overview.

Then issues went south. Because the article’s headline put it, “[T]his tech millionaire went from Covid trial funder to misinformation superspreader.”

Now we will add the phrase “creep” to his CV.

Final week, on a Delta Air Traces flight, Kirsch supplied a close-by feminine passenger $100,000 to take away her face masks all through the flight.

“I’m on board a Delta flight proper now,” he stated in a put up on social media.  “The individual sitting subsequent to me in first-class refused $100,000 to take away her masks for your complete flight. No joke. This was after I defined they don’t work. She works for a pharma firm.”

Apparently she didn’t purchase into his rationalization of how masks don’t work the identical approach individuals voiced skepticism about an article that lately appeared within the Cochrane Overview that led many to conclude that masks don’t work to stop SARS-CoV-2.  In early March, the publication’s editor apologized for the article, calling the conclusion that masks don’t work “inaccurate.”

Kirsch continued to harass the passenger, who remained nameless, all through the flight.

“I began the bidding at $100,” Kirsch stated on Twitter. “And I identified that when she eliminated the masks for consuming and consuming, she could possibly be contaminated with one breath. So she had full disclosure.”

“She took off her masks as quickly because the breakfast was served!!!! As a result of everybody is aware of you’ll be able to’t get contaminated while you’re consuming!! ,” he sarcastically added, earlier than concluding his rant: “Perhaps subsequent time I’ll sit subsequent to somebody who had an account at Silicon Valley Financial institution.”

Quite a few individuals on Twitter known as Kirsch a “creep” and a “noxious boastful idiot.”

“Harassed a lady minding her personal enterprise in a confined house the place she couldn’t get away from you… Beautiful,” one other poster wrote.

In different information we cowl at present, the U.S. maternal mortality price hit its highest degree in virtually 60 years, an current MS drug could function an antiviral for Covid, and Paxlovid doesn’t seem to trigger Covid rebound.


The Meals and Drug Administration launched a report that reveals that there is no such thing as a clear affiliation between use of the antiviral Paxlovid and Covid rebound.  Rebound charges, the examine stated, have been roughly the identical in individuals who took the drug and in those that didn’t.

“Virologic and/or symptomatic rebound could happen as a part of the pure development and determination of COVID-19 illness, regardless of Paxlovid therapy,” the FDA wrote. Roughly 10 to 16% of individuals with SARS-CoV-2 had rebound signs, in keeping with the FDA’s evaluation.

In the meantime, the U.S. maternal mortality price hit its highest degree in virtually 60 years in 2021. The variety of girls who died throughout being pregnant or shortly thereafter within the calendar 12 months 2021 rose 40% to 1,205, in contrast with 861 in 2020 and 754 in 2019, the Nationwide Heart for Well being Statistics stated Thursday.

Lastly, a brand new T cell antibody therapy is claimed to improves outcomes in sufferers with SARS-CoV-2. T cells are one of many essential forms of white blood cells of the immune system and play a central position within the adaptive immune response.

A brand new examine revealed within the journal PNAS, the Proceedings of the Nationwide Academy of Sciences of america, means that the drug Foralumab, designed to deal with a number of sclerosis and different neurodegenerative illnesses, could forestall an infection in these lately uncovered to the virus and may also assist sufferers with the virus  stave off the worst results of Covid-19.


The World Well being Group’s plan to create a community of mRNA “vaccine hubs” in third-world international locations for the aim of sharing expertise and finally manufacturing mRNA vaccines of their very own would require funding from america, the company stated. The World Financial institution’s pandemic fund has to date raised some $1.6 billion, with $300 million accessible for a primary spherical of financing for pandemic preparedness efforts.


Now listed here are the every day statistics for Thursday, March 16.

As of Thursday morning, the world has recorded 682.1 million Covid-19 instances, a rise of 0.3 million from the day prior to this, and just below 6.82 million deaths, in keeping with Worldometer, a service that tracks such data. As well as, 655 million individuals worldwide have recovered from the virus, a rise of 0.1 million.

The reader ought to be aware that rare reporting from some sources could seem as spikes in new case figures or loss of life tolls.

Worldwide, the variety of lively coronavirus instances as of Thursday at press time is 20,240,530, a rise of 136,000. Out of that determine, 99.8%, or 20,200,243, are thought-about delicate, and 0.2%, or 40,287, are listed as essential. The proportion of instances thought-about essential has not modified over the previous three months.

The USA reported 20,174 new coronavirus infections on Wednesday for the day prior to this, in comparison with 13,115  reported on Tuesday, 1,005  reported on Monday, 1,489 reported on Sunday, 10,161 reported on Saturday, and 55,447 reported on Friday, in keeping with information from the U.S. Division of Well being and Human Companies. The 7-day incidence price is now 28,313.  Figures for the weekend (reported the next day) are usually 30% to 60% of these posted on weekdays resulting from a decrease variety of checks being carried out.

The common every day variety of new coronavirus instances in america over the previous 14 days is 27,442, a determine down 18% over the previous 15 days, primarily based on information from the Division of Well being and Human Companies, amongst different sources.  The common every day loss of life toll over the identical interval is 414, a lower of 19% over the identical interval, whereas the typical variety of hospitalizations for the interval was 23,112, a lower of 14%. As well as, the variety of sufferers in ICUs was 3,084, a lower of 12% and the check positivity price is now 7.3%, a determine that’s down by 13% over the identical interval.

As well as, for the reason that begin of the pandemic america has, as of Thursday, recorded 105.7 million instances, a better determine than another nation, and a loss of life toll of 1.15 million. India has the world’s second highest variety of formally recorded instances, 44.7 million, and a reported loss of life toll of 530,790.

The most recent information from Russia’s Rosstat state statistics service confirmed that, on the finish of July, the variety of Covid or Covid-related deaths for the reason that begin of the pandemic there in April 2020 is now 823,623, giving the nation the world’s second highest pandemic-related loss of life toll, behind america.  Rosstat final reported that 3,284 individuals died from the coronavirus or associated causes in July 2022, down from 5,023 in June, 7,008 in Could and 11,583 in April.

In the meantime, France is the nation with the third highest variety of instances, with 39.7 million, and Germany is within the quantity 4 slot, with 38.3 million whole instances.

Brazil, which has recorded the third highest variety of deaths because of the virus, 699,634, has recorded 37.1 million instances, putting it within the quantity 5 slot.

The opposite 5 international locations with whole case figures over the 20 million mark are Japan, with over 33.3 million instances, South Korea, with just below 30.7 million instances, putting it within the quantity seven slot, and Italy, with simply over 25.6 million, as quantity eight, in addition to the UK, with 24.4 million, and Russia, with just below 22.5 million.


The Facilities for Illness Management and Prevention stated that, as of the previous Thursday, 269.6 million individuals in america – or 81.2% – have acquired no less than one dose of the coronavirus vaccine. Of that inhabitants, 69.3%, or 230.1 million individuals, have acquired two doses of vaccine, and the entire variety of doses which have been disbursed in america is now 672.1 million. Breaking this down additional, 92.1% of the inhabitants over the age of 18 – or 237.8 million individuals – has acquired no less than a primary inoculation and 79% of the identical group – or simply underneath 204 million individuals – is totally vaccinated.  As well as, 19.6% of the identical inhabitants, or 50.5 million individuals, has already acquired an up to date or bivalent booster dose of vaccine, whereas 22.7 million individuals over the age of 65, or 41.4% of that inhabitants have additionally acquired the bivalent booster.

Beginning on June 13, 2022, the CDC started to replace vaccine information on a weekly foundation and publish the up to date data on Thursdays by 8 p.m. EDT, a press release on the company’s web site stated.

Some 69.7% of the world inhabitants has acquired no less than one dose of coronavirus vaccine by Thursday, in keeping with Our World in Knowledge, an internet scientific publication that tracks such data.  Up to now, 13.33 billion doses of the vaccine have been administered on a worldwide foundation and 389,899 doses at the moment are administered every day.

In the meantime, solely 28.3% of individuals in low-income international locations have acquired one dose, whereas in international locations similar to Canada, China, Denmark, France, Italy, the UK, and america, no less than 75% of the inhabitants has acquired no less than one dose of vaccine.

Solely a handful of the world’s poorest international locations – Bangladesh, Bhutan, Cambodia and Nepal – have reached the 70% mark in vaccinations. Many international locations, nonetheless, are underneath 20% and, in international locations similar to Haiti, Senegal, and Tanzania, for instance, vaccination charges stay at or under 10%.

As well as, with the beginning of vaccinations in North Korea in late September, Eritrea stays the one nation on this planet that has not administered vaccines.

Anna Breuer contributed reporting to this story.

(Photograph: Accura Media Group)



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